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　　吴苗苗，湖南农业大学，师从印遇龙院士，湖南省百人方案青年人才。

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一、教育阅历

　　2015.1-2018.12 博士，兽医病理生物学，堪萨斯州立大学，美国

红财经配资,红财经配资

　　2011.8-2014.7 硕士, 动物养分与饲料科学，我国科学院大学，我国

110013,110013

　　2007.8-2011.7 本科，动物医学，西南大学，我国

　　2008.8-2011.7 本科，英语（第二专业），西南大学，我国

吴苗苗，湖南农业大学，师从印遇龙院士，湖南百人方案青年人才。

二、荣誉奖赏

　　2018：Samuel M.Kruckenberg奖学金

　　2018：研讨生院学术游览奖赏，堪萨斯州立大学

　　2018：兽医系学术游览奖赏，堪萨斯州立大学

　　2014：优异硕士毕业论文，我国科学院大学

　　2014：优异毕业生，我国科学院大学

　　2014：中科院广州教育基地第十三届研讨生学术陈述会硕士组三等奖，我国科学院大学研讨生学术论坛广州分会

　　2009：国家本科生科技立异基金项目，西南大学

　　2009：国家勉励奖学金，西南大学

湖南农业大学

三、科研阅历

　　1、博士后：2019.1-至今 导师：Sherry Fleming教授

　　Postdoc Fellowship，Division of Biology, Kansas State University, Manhattan, KS [美国]

　　研讨方向：不同性别肠缺血再灌注损害的机制差异

　　2、博士研讨生：2015.1-2018.12 导师：Philip R. Hardwidge教授

　　Graduate Research Assistant，Department of Diagnostic Medicine /Pathobiology, Kansas State University, Manhattan, KS [美国]

　　研讨方向：肠道致病菌III型分泌系统毒力效应蛋白对NF-kappaB信号途径的机制研讨

　　3、硕士研讨生：2011.8-2014.7 导师：印遇龙院士、李铁军研讨员

　　动物养分与饲料科学，我国科学院大学，北京，我国

　　研讨方向：谷氨酸缓解吐逆毒素对仔猪毒害效果的研讨

　　4、大学本科：2007.9-2011.7 导师：彭远义教授、王豪举教授

　　动物医学，西南大学，重庆，我国

　　研讨方向：混合感染模型中大肠杆菌诱生抗原基因的开始研讨

湖南农业大学

四、论文

　　（一）宣布SCI录入文章（ Google Scholar检索陈述 2018. 09. 24）

　　1、Wu, M.M., H. Xiao, G. Liu, S. Chen, B.E. Tan, W.K. Ren, F.W. Bazer, G.Y. Wu, and Y.L. Yin. Glutamine promotes intestinal SIgA secretion through intestinal microbiota and IL-13. Molecular Nutrition & Food Research. 2016, 60, 1637-1648. （Top Journal, Front Cover） citations: 20 （2017 IF: 5.151）一区

　　2、Xiao, H.*, M.M. Wu*, F.Y. Shao, G.P. Guan, B. Huang, B.E. Tan, and Y.L. Yin. N-Acetyl-L-cysteine protects the enterocyte against oxidative damage by modulation of mitochondrial function. Mediators of Inflammation. 2016, 2016, 8364279. （*平等奉献） citations: 1 （2017 IF: 3.549）二区

　　3、Xiao, H.*, M.M. Wu*, F.Y. Shao, B.E. Tan, T.J. Li, W.K. Ren, J. Yin, J. Wang, Q.H. He, Y.L. Yin, and Y.Q. Hou. Metabolic profiles in the response to supplementation with composite antimicrobial peptides in piglets challenged with deoxynivalenol. Journal of Animal Science. 2015, 93, 1114-1123. （*平等奉献） （Top Journal） citations: 10 （2017 IF: 1.711） 一区

　　4、Yin, J.*, M.M. Wu*, J.L. Duan, G. Liu, Z.J. Cui, J. Zheng, S. Chen, W.K. Ren, J.P. Deng, X.W. Tan, N.A. Al-Dhabi, V. Duraipandiyan, P. Liao, T.J. Li, and Y.L. Yin. Pyrrolidine dithiocarbamate inhibits NF-κB activation and upregulates the expression of Gpx1, Gpx4, occludin, and ZO-1 in DSS-Induced Colitis. Applied Biochemistry and Biotechnology. 2015, 177, 1716-1728. （*平等奉献） citations: 14 （2017 IF: 1.797）三区

　　5、Wu, M.M., H. Xiao, W.K. Ren, J. Yin, J.Y. Hu, J.L. Duan, G. Liu, B.E. Tan, X. Xiong, A.O. Oso, O. Adeola, K. Yao, Y.L. Yin, and T.J. Li. An NMR-based metabolomic approach to investigate the effects of supplementation with glutamic acid in piglets challenged with deoxynivalenol. PLoS One. 2014, 9, e113687. citations: 11 （2017 IF: 2.766）一区

　　6、Wu, M.M., H. Xiao, W.K. Ren, J. Yin, G. Liu, L.L. Li, C.M. Nyachoti, T.J. Li, Y.L. Yin, G.Y. Wu. Therapeutic effects of glutamic acid in piglets challenged with deoxynivalenol. PLoS One. 2014, 9, e100591. citations: 34 （2017 IF: 2.766）一区

　　7、Wu, M.M., J.M. Rowe, S.D. Fleming. Eicosanoid production varies by sex in mesenteric ischemia reperfusion injury. Clinical immunology. 2020（已接纳）（2018 IF: 3.368）二区

　　8、Wu, M.M., H. Xiao, F.Y. Shao, B.E. Tan, S.L. Hu. Arginine accelerates intestinal health through cytokines and intestinal microbiota. International Immunopharmacology. 2020, 81, 106029. （ 2018 IF: 3.361） 三区

　　9、Wu, M.M. and P.R. Hardwidge. Hsp90 interacts with the bacterial effector NleH1. Pathogens, 2018. 7（4）. （2018 IF: 3.405）二区

　　10、Wu, M.M., S. El Qaidi, and P.R. Hardwidge. SseL deubiquitinates RPS3 to inhibit its nuclear translocation. Pathogens, 2018. 7（4）. （2018 IF: 3.405）二区

　　11、Yin, J.*, M.M. Wu*, Y.Y. Li, W.K. Ren, H. Xiao, S. Chen, C.Y. Li, B.E. Tan, H.J. Ni, X. Xiong, Y.Z. Zhang, X.G. Huang, R.J. Fang, T.J Li, and Y.L. Yin. Toxicity assessment of hydrogen peroxide on Toll-like receptor system, apoptosis, and mitochondrial respiration in piglets and IPEC-J2 cells. Oncotarget. 2017, 8, 3124-3131. （*平等奉献） citations: 3 （2017 IF: 5.168）

　　12、El Qaidi, S., M.M. Wu, C.R. Zhu, and P.R. Hardwidge. Salmonella, E. coli, and Citrobacter type III secretion system effector proteins that alter host innate immunity. Advances in Experimental Medicine and Biology. 2018. （2016 IF: 1.881）

　　13、Park, J.B., Y.H. Kim, Y.K. Yoo, J.Y. Kim, S.H. Jun, J.W. Cho, S. El Qaidi, S. Walple, S. Monaco, A. Garcia-Garcia, M.M. Wu, M.P. Hays, R.H. Guerrero, J. Angulo, P.R. Hardwidge, J.S. Shin, and H.S. Cho. Structural basis for arginine glycosylation of host proteins by bacterial effector proteins. Nature Communications. 2018, 9, 4283. （2017 IF: 12.353）一区

　　14、He, F., Z. Yin, C.L. Wu, Y.Y. Xia, M.M. Wu, P. Li, H.H. Zhang, Y.Y. Yin, N.Z. Li, G.Q. Zhu, W.K. Ren, Y.Y. Peng. L-serine lowers lung inflammatory responses during Pasteurella multocida infection, Infection and Immunity. 2020, 87, 12. （2018 IF: 3.16） 三区

　　15、Xiao, H., L.M. Zeng, F.Y. Shao, B. Huang, M.M. Wu, B.E. Tan, and Y.L. Yin. The role of nitric oxide pathway in arginine transport and growth of IPEC-1 cells. Oncotarget. 2017, 8, 29976–29983. citations: 2 （2017 IF: 5.168）

　　16、Xiong, X., H.S. Yang, B.E. Tan, C.B. Yang, M.M. Wu, G. Liu, W.S. Kim, T.J. Li, L.L. Li, J.J. Wang, G.Y. Wu, and Y.L. Yin. Differential expression of proteins involved in energy production along the crypt-villus axis in early-weaning pig small intestine. American Journal of Physiology Gastrointestinal and Liver Physiology. 2015, 309, G229-237. citations: 25 （2016 IF: 3.468）

　　17、Xiao, H.*, F.Y. Shao*, M.M. Wu, W.K. Ren, X. Xiong, B.E. Tan, and Y.L. Yin. The application of antimicrobial peptides as growth and health promoters for swine. Journal of Animal Science and Biotechnology. 2015, 6, 19. （*equal contribution） citations: 22 （2017 IF: 3.205）

　　18、Xiao, H., B.E. Tan, M.M. Wu, F.Y. Shao, and Y.L. Yin. Regulatory Mechanism of mTOR Signaling Pathway on Cell Energy Metabolism. SCIENTIA SINICA Vitae. 2015, 45, 1124-31. citations: 1

　　19、Wang, J., G.R. Li, B.E. Tan, X, Xiong, X.F. Kong, D.F. Xiao, L.W. Xu, M.M. Wu, B. Huang, S.W. Kim, and Y.L. Yin. Oral administration of putrescine and proline during the suckling period improves epithelial restitution after early weaning in piglets. Journal of Animal Science. 2015, 93, 1679-1688. （Top Journal） citations: 23 （2017 IF: 1.711）一区

　　20、Yin, J., W.K. Ren, H.Q. Hou, M.M. Wu, H. Xiao, J.L. Duan, Y.R. Zhao, T.J. Li, Y.L. Y.L. Yin, G.Y. Wu, and C.M. Nyachoti. Use of homoarginine for measuring true ileal digestibility of amino acids in food protein. Amino Acids. 2015, 47, 1795-1803. citations: 7 （2017 IF: 2.906）

　　21、Duan, J.L., J. Yin, W.K. Ren, M.M. Wu, S. Chen, Z.J. Cui, X. Wu, R.L. Huang, T.J. Li, and Y.L. Yin. Pyrrolidine dithiocarbamate restores gastric damages and suppressive autophagy induced by hydrogen peroxide. Free Radical Research. 2015, 49, 210-218. citations: 6 （2017 IF: 3.038）

　　22、Duan JL*, J. Yin*, M.M. Wu, P. Liao, D. Deng, G. Liu, Q.Q. Wen, Y.F. Wang, W. Qiu, Y. Liu, X.L. Wu, W.K. Ren, B.E. Tan, M.H. Chen, H. Xiao, L. Wu, T.J. Li, C.M. Nyachoti, O. Adeola, and Y.L. Yin. Dietary glutamate supplementation ameliorates mycotoxin-induced abnormalities in the intestinal structure and expression of amino acid transporters in young pigs. PLoS one. 2014, 9, e112357. （*equal contribution） citations: 26 （2017 IF: 2.766）一区

　　23、Ren, W.K. *, J. Yin*, M.M. Wu, G. Liu, G. Yang, Y. Xiong, D. Su, L. Wu, T.J. Li, S. Chen, J.L. Duan, Y.L. Yin, and G.Y. Wu. Serum amino acids profile and the beneficial effects of L-arginine or L-glutamine supplementation in dextran sulfate sodium colitis. PLoS One. 2014, 9, e88335. citations: 90 （2017 IF: 2.766）一区

　　24、Yin, J., M.M. Wu, H. Xiao, W.K. Ren, J.L. Duan, G. Yang, T.J. Li, and Y.L. Yin. Development of an antioxidant system after early weaning in piglets. Journal of Animal Science. 2014, 92, 612-619. （Top Journal） citations: 90 （2017 IF: 1.711）一区

　　25、Ren, W.K., W. Luo, M.M. Wu, G. Liu, X.L. Yu, K. Yao, T.J. Li, Y.L. Yin, and G.Y. Wu. Dietary L-glutamine supplementation improves pregnancy outcome in mice infected with type-2 porcine circovirus. Amino Acids. 2013, 45, 479–488. citations: 69 （2017 IF: 2.906）

　　26、Ren, W.K., R. Yu, G. Liu, N.Z. Li, Y.Y. Peng, M.M. Wu, Y.L. Yin, Y.H. Li, A. Andrew. A.A. Fatufe, and T.J. Li. DNA vaccine encoding the major virulence factors of Shiga toxin type 2e （Stx2e）-expressing Escherichia coli induces protection in mice. Vaccine. 2013, 31, 367-372. citations: 18 （2017 IF: 3.285）

　　27、Ren, W.K., M.M. Wu, W. Luo, R. Huang, Y.L. Yin, Y.H. Li, T.J. Li, and X.L. Yu. Dietary supplementation with proline confers a positive effect in both porcine circovirus-infected pregnant and non-pregnant mice. British Journal of Nutrition. 2013, 110, 1492-1499. citations: 13 （2017 IF: 3.657）

　　28、Xiao, H., M.M. Wu, B.E. Tan, Y.L. Yin, T.J. Li, D.F. Xiao, and L. Li. Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: I. Growth performance, immune function, and antioxidation capacity. Journal of Animal Science. 2013, 91, 4772-4780. （Top Journal） citations: 46 （2017 IF: 1.711）一区

　　29、Xiao, H., M.M. Wu, B.E. Tan, Y.L. Yin, T.J. Li, D.X. Yuan, and L. Li. Effects of composite antimicrobial peptides in weanling piglets challenged with deoxynivalenol: II. Intestinal morphology and function. Journal of Animal Science. 2013, 91, 1-7. （Top Journal） citations: 42 （2017 IF: 1.711）一区

　　（二）待宣布SCI论文

　　30. He, F., C.L. Wu, Y.Y. Xia, S.Y. Chen, H.H. Zhang, Y.Y. Yin, N.Z. Li, W.K. Ren, Y.Y. Peng, M.M. Wu. L-serine lowers lung inflammatory responses in mice during Pasteurella multocida infection, Submitted to The Journal of Immunology, under review. （Top Journal） （2017 IF: 4.539） 一区

　　31. Wu, M.M., S.D. Fleming. Complement activation delay causes decreased intestinal ischemia-reperfusion injury in female mice. Submitted to The Journal of Immunology, under review. （Top Journal） （2017 IF: 4.539） 一区

　　（三）宣布论文（中文中心期刊）

　　1、黄博，胡佳宇，吴苗苗，肖昊，张军，谭碧娥, 印遇龙. 猪胃肠道谷氨酸代谢及其对机体健康的影响[J]. 动物养分学报, 2015, 27（11）: 3326-3331.

　　2、吴苗苗, 肖昊, 印遇龙, 李丽立, 李铁军. 谷氨酸对脱氧雪腐镰刀菌烯醇影响下的断奶仔猪成长功用、血常规及血清生化目标改变的干涉效果 [J]. 动物养分学报, 2013, 25（7）: 1587-1594.

　　3、陈明洪，尹杰，邓建文，吴苗苗，肖昊，段杰林，方俊，李铁军. 氨基酸对吐逆毒素诱导的肥育猪血液生理生化损害的干涉效应[J]. 湖南农业科学, 2013, 7: 112-116.

　　4、段杰林，尹杰，吴苗苗，陈明洪，肖昊，何绍平，李颖悟，王磊，黄兴国，张彬，李铁军. 脱氧雪腐镰刀菌烯醇对肠道结构与免疫功用的影响及机理 [J]. 生命科学, 2013, 25（4）: 402-409.

　　5、黄分明*，吴苗苗*，陈友梅，刘汉超，崔亚蓝，李能章，王豪举. 鸡大肠杆菌和沙门氏菌混合感染模型的构建[J]. 我国兽医杂志, 2012, 48: 49-51.（*平等奉献）

　　6、吴苗苗，黄分明，陈友梅，李能章，王豪举. 细菌体内诱生抗原挑选技能的研讨发展[J]. 动物医学发展, 2011, 32（4）: 90-94.

四、专著教材

　　1、Handbook of Livestock and poultry production. 2012, Hunan Science & Technology Press. （Coauthor） （Chinese）

五、会议摘要，海报和口头陈述

　　1、Wu, M.M. and P.R. Hardwidge. SseL deubiquitinates RPS3 to inhibit its nuclear translocation. The 99th, Annual Conference of Research Workers in Animal Disease （CRWAD）. Chicago, IL, USA, Dec 1-4, 2018. （口头陈述）

　　2、Wu, M.M. and P.R. Hardwidge. SseL functions as a deubiquitinase to inhibit RPS3 nuclear translocation. 17th Annual Great Plains Infectious Disease Meeting. Lawrence, KS, Nov 4-5, 2018. （会议海报）

　　3、Wu, M.M. and P.R. Hardwidge. Do T3SS effectors other than NleH1 inhibit RPS3 nuclear translocation? 15th Annual Great Plains Infectious Disease Meeting. Lawrence, KS, Nov 4-5, 2016. （会议海报）

　　4、Xiao, H., M.M. Wu, F.Y. Shao, B. Huang, B.E. Tan, and Y.L. Yin. N-acetyl-L-cysteine （NAC） protects the enterocyte against oxidative damage by preserving mitochondrial function. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. Changsha, HN, Oct 19-21, 2012. （会议摘要）

　　5、Wu, M.M., H. Xiao, Y.L. Yin, L.L. Li, and T.J. Li. Effects of glutamic acid in piglets challenged with deoxynivalenol on intestinal morphology, D-lactate and DAO. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. Changsha, HN, Oct 19-21, 2012. （会议摘要）

　　6、Wu, M.M., H. Xiao, L. Wu, Y.L. Yin, L.L. Li, and T.J. Li. Effects of glutamic acid in piglets challenged with deoxynivalenol on growth performance and antioxidation capacity. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. Changsha, HN, Oct 19-21, 2012. （会议摘要）

　　7、Wu, M.M., H. Xiao, Y.L. Yin, L.L. Li, and T.J. Li. Metabolism of glutamic acid by gastrointestinal tract. The International Academic Conference hosted by the Coalition on National Swine Industrial Technology Innovation. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. , Changsha, HN, Oct 19-21, 2012. （会议摘要）

　　8、Xiao, H., M.M. Wu, Y.L. Yin, B.E. Tan, and T.J. Li. Restore effects of composite antimicrobial peptide in deoxynivalenol-induced intestinal injury in piglet. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. Changsha, HN, Oct 19-21, 2012. （会议摘要）

　　9、Xiao, H., M.M. Wu, Y.L. Yin, B.E. Tan, and T.J. Li. Effects of composite antimicrobial peptide on alleviation of deoxynivalenol toxicity in piglets. The 11th National Animal Nutrition Symposium of Animal Nutrition Branch of Chinese Association of Animal Science and Veterinary Medicine. Changsha, HN, Oct 19-21, 2012. （会议摘要）

湖南农业大学

六、特邀审稿人

　　1、Research of Veterinary Science: 2019-至今

　　2、esearch in Veterinary Science: 2018-至今

　　3、Medical Science Monitor: 2018-至今

　　4、Toxicology Reports: 2017-至今

我国各农业大学教授简介

　　贺建华，湖南农业大学教授、博导，饲料作物出产使用博士点领衔人

　　刘秀斌，湖南农业大学，博士，讲师，饲料添加剂专家

　　陈东（女），湖南农业大学，博士、讲师，牛羊饲草专家

　　刘武军（女），新疆农业大学教授、博导，动科院遗传育种系主任

　　高泽霞（女），华中农业大学教授、博士，水产专家，湖北杰出青年

　　杜晓惠（女），四川农业大学教授、博士，家禽遗传育种与繁衍专家

　　钟元春（女），博士，讲师，湖南农业大学，畜牧环保专家

　　宋泽和，博士，湖南农业大学，家禽养分专家

　　阿布力孜·吾斯曼，维吾尔族，新疆农业大学教授，动物科学院书记